In Observance of U.S. Holiday, Thanksgiving, Agilent Cross Lab/ iLab Operations Software Support Help Desk will be closed during U.S. hours on Thursday November 26th and Friday November 27th, 2020. We will resume regular U.S. support hours on Monday November 30th, 2020. EU and APAC Support will remain open during this time. For urgent matters, please add "Urgent" to the ticket/ email subject or press "1", when prompted, to escalate a call on the iLab Support phone and we will prioritize those requests first.

Genetically Engineered Rodent Models Core

About Us

The Genetically Engineered Rodent Models (GERM) Core possesses specialized expertise and state-of-the-art equipment for providing essential mouse services to investigators at Baylor College of Medicine and collaborative investigators of other institutes. Our Core assists investigators with projects involving the production of transgenic, targeted knockout, and targeted knock-in mouse lines. Knockout and knock-in mouse lines can be generated using gene targeting in embryonic stem (ES) cells with chimera production or CRISPR genome editing in mouse zygotes. For projects involving CRISPR genome editing, the GERM Core offers a genome editing design service (guide selection, donor DNA design, and genotyping design) in addition to an on- and off-target mutagenesis genotyping service. The GERM Core also performs cryopreservation of mouse embryos and sperm for long-term storage of mouse lines, mouse line rederivation, in vitro fertilization, and mouse colony expansion.



Cryopreservation and Embryology


 Traditional Gene Targeting

 CRISPR/Cas9 Genome Editing

 CRISPR/Cas9 Genotyping

Customized Services

Please contact the GERM Core at to discuss a project that may not fall within our listed service categories.


Getting Started

  • BCM Users:  Click the link in the upper right corner to login or register for an iLab account using valid BCM credentials.
  • Non-BCM Users:  Click the appropriate link in the upper right corner to login with your approved iLab credentials or to sign up for an iLab account.



Jason Heaney, Ph.D. | Core Director

Phone: (713) 798-1778



Location and Hours of Operation



Genetically Engineered Rodent Model Core

Baylor College of Medicine, Mail Stop BCM 227

One Baylor Plaza, Houston, TX 77030

Phone:  (713) 798-1981

Fax:  (713) 798-7418

7 a.m. - 4 p.m., Monday to Friday




Links and Resources


Publication Acknowledgements

Scientific publications containing data obtained using the services offered by the core should include the following statement in the acknowledgment section: This project was supported by the Genetically Engineered Rodent Model Core at BCM.



Name Role Phone Email Location
Jason Heaney, Ph.D.
Academic Director
(713) 798-1778

Internal BCM iLab Support
Internal BCM iLab Support

Lan Liao, MS
Technical Director
(713) 798-5278

Isabel Lorenzo, BS
Mouse Model Production Manager
(713) 798-1981

Denise Lanza, Ph.D.
CRISPR Project Manager
(713) 798-3115