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Genetically Engineered Rodent Models Core

About Us

The Genetically Engineered Rodent Models (GERM) Core possesses specialized expertise and state-of-the-art equipment for providing essential mouse services to investigators at Baylor College of Medicine and collaborative investigators of other institutes. Our Core assists investigators with projects involving the production of transgenic, targeted knockout, and targeted knock-in mouse lines. Knockout and knock-in mouse lines can be generated using gene targeting in embryonic stem (ES) cells with chimera production or CRISPR genome editing in mouse zygotes. For projects involving CRISPR genome editing, the GERM Core offers a genome editing design service (guide selection, donor DNA design, and genotyping design) in addition to an on- and off-target mutagenesis genotyping service. The GERM Core also performs cryopreservation of mouse embryos and sperm for long-term storage of mouse lines, mouse line rederivation, in vitro fertilization, and mouse colony expansion.

 

Services

Cryopreservation and Embryology

 Transgenics

 Traditional Gene Targeting

 CRISPR/Cas9 Genome Editing

 CRISPR/Cas9 Genotyping

Customized Services

Please contact the GERM Core at germcore@bcm.edu to discuss a project that may not fall within our listed service categories.

 

Getting Started

  • BCM Users:  Click the link in the upper right corner to login or register for an iLab account using valid BCM credentials.
  • Non-BCM Users:  Click the appropriate link in the upper right corner to login with your approved iLab credentials or to sign up for an iLab account.

  

Leadership

Jason Heaney, Ph.D. | Core Director

Phone: (713) 798-1778

Email: heaney@bcm.edu

 

Location and Hours of Operation

Location

 Hours

Genetically Engineered Rodent Model Core

Baylor College of Medicine, Mail Stop BCM 227

One Baylor Plaza, Houston, TX 77030

Phone:  (713) 798-1981

Fax:  (713) 798-7418

7 a.m. - 4 p.m., Monday to Friday

 

 

 

Links and Resources

 

Publication Acknowledgements

Scientific publications containing data obtained using the services offered by the core should include the following statement in the acknowledgment section: This project was supported by the Genetically Engineered Rodent Model Core at BCM.

 

Contacts

Name Role Phone Email Location
Jason Heaney, Ph.D.
Academic Director
 
(713) 798-1778
 
heaney@bcm.edu
 

 
Internal BCM iLab Support
Internal BCM iLab Support
 

 
ilabs-support@bcm.edu
 

 
Lan Liao, MS
Technical Director
 
(713) 798-5278
 
lliao@bcm.edu
 

 
Isabel Lorenzo, BS
Mouse Model Production Manager
 
(713) 798-1981
 
isabell@bcm.edu
 

 
Denise Lanza, Ph.D.
CRISPR Project Manager
 
(713) 798-3115
 
denise@bcm.edu