Mouse Embryonic Stem Cell Core

Overview of Services


Welcome to the Mouse ES Cell Core Facility at Baylor College of Medicine.


Advanced technologies are used at the Mouse ES Cell Core Facility to generate genetically engineered mice needed by researchers across the United States who are in pursuit of answers and cures for human disease.


Our facility serves to assist investigators with projects that involve generating mutations in the germ line and somatic tissues of mice by performing homologous recombination in ES cells. The procedures for the manipulation of ES cells and the construction of mice are intensive and technically demanding and it is a goal of the core to make such experiments possible for investigators.


Embryonic Stem Cell Culture Services:

  • Electroporation
  • ROSA Targeting
  • CRISPR Targeting
  • Clone Expansion
  • Generation of primary mouse ES cell lines
  • Murine Virus Testing


          CRISPR Services:

  • Design to DNA template production
  • RNA production
  • Homology Directed Repair donor DNA design and production


          Coming Soon:

  • Genotyping


Projects are scheduled on a first-come-first-serve basis after approval from the director. Read core guidelines and use the online forms on the Request Services tab to get started. (One-time registration is required to set up your account.)





Getting Started


  • BCM Users:  Click the link in the upper right corner to login or register for an iLab account using valid BCM credentials.


  • Non-BCM Users:  Click the appropriate link in the upper right corner to login with your approved iLab credentials or to sign up for an iLab account.






Jason Heaney, Ph.D. | Core Director

Phone: (713) 798-1778




Location and Hours of Operation



Mouse Embryonic Stem Cell Core

Baylor College of Medicine, Mail Stop BCM 227

One Baylor Plaza, Houston, TX 77030

Phone:  (713) 798-1981

Fax:  (713) 798-7418

7 a.m. - 4 p.m., Monday to Friday




Links and Resources




Publication Acknowledgements


Scientific publications containing data obtained using the services offered by the core should include the following statement in the acknowledgment section: This project was supported by the Mouse Embryonic Stem Cell Core at BCM.



Name Role Phone Email Location
Isabel Lorenzo
Technical Director
(713) 798-1981

Jason Heaney, Ph.D.
Academic Director
(713) 798-1778

Internal BCM iLab Support
Internal BCM iLab Support

Denise Lanza, Ph.D.
Manager CRISPR Technologies


Service Price List

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